TOWARDS ENHANCED GAS SENSOR PERFORMANCE WITH FLUOROPOLYMER MEMBRANES


A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy.

Gemcitabine is among the most efficacious and widely used antimetabolite agents.Its molecular targets are ribonucleotide reductase M1 (RRM1) and elongating DNA.Acquired and de novo resistance as a result of RRM1 overexpression are major obstacles to therapeutic efficacy.We deployed a synthetic lethality screen to investigate if knockdown of 87 sele

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Intracoronary tenecteplase in STEMI with massive thrombus

Primary percutaneous coronary intervention is the current standard of care in ST elevation myocardial infarction (STEMI).However, large thrombus is an independent predictor for stent thrombosis and major adverse cardiac events in patients undergoing primary angioplasty for STEMI.Here we report a BIFIDUS series of STEMI patients with large thrombus

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Metagenomic analysis of captive Amur tiger faecal microbiome

Abstract Background The gastrointestinal tracts of animals are home to large, complex communities of microbes.The compositions of these communities ultimately reflect the coevolution of microorganisms with their animal host and are influenced by the living environment, diet and immune status of the host.Gut microbes have been shown to be important

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